To explore whether α7nAChR is expressed in keratinocytes, we compared the expression of α7nAChR in HaCaT cells, an immortalized human keratinocyte line, to THP-1 cells, a human monocytic cell line derived from an acute monocytic leukemia patient that has been reported to positively express α7nAChR [9], thus were used as positive control. The gene discussed is CHRNA7; the disease is acute monocytic leukemia.