The cancer-promoting role of MEIS1 involves promoting leukemogenesis and leukemic cell homing and enhancing cell-cell interactions and cell migration.6 Regarding its tumor-suppressive effects, MEIS1 inhibits the proliferation of non-small-cell lung cancer and prostate cancer cells;7 while the mechanism behind this tumor-suppressor role is largely unknown. The gene discussed is MEIS1; the disease is cancer.