The transcriptomic profiles of CD4+ T cells in effector-state (including CD4+ Effector Memory, CD4+ Effector-GZMK, CD4+ Effector-GNLY, NKT-like, CD4+ IFN, and CD4+ Exhausted clusters) were compared between the TP or ART and HD conditions. This evidence concerns the gene IFNA1 and Huntington disease.