In this subset, the deep learning MRI score classified prodromal AD with an AUROC = 0.815 (ACC = 78.6%), compared to the AUROC of 0.782 for PDG-PET (ACC = 75.4%) and 0.751 (ACC = 71.4%) for amyloid-PET, although the differences were not statistically significant (Fig. 3, bottom panel). Here, PHGDH is linked to Alzheimer disease.