Groele et al. compared the dose of prandial insulin calculated based on the individual patient’s ICR with the dose increased by about 30% for an h-GI meal and concluded that the frequencies of PPH and hypoglycemia were similar in both groups, but the additional dose of insulin significantly reduced glucose excursion in terms of the mean postprandial glycemia (47.4 ± 39.8 mg/dl vs 76.2 ± 58.2 mg/dl) [22]. Here, INS is linked to Hypoglycemia.