KRAS and neoplasm: As shown in Figure S4, the OS of low-risk patients based on age (p-value < 0.001), gender (p-value = 0.003 in male), tumor location (p-value = 0.008 in left-side and p-value = 0.040 in right side), TNM stage (p-value = 0.045 in stage I-II and p-value < 0.001 in stage III-IV), and KRAS mutation (p-value = 0.022 in yes and p-value = 0.028 in no) was significantly higher than that of high-risk patients.