In this retrospective study, we performed a systematic assessment of MP effect by use of a set of well-studied COVID-19 severity biomarkers including CRP, d-dimer, albumin (Alb), and Krebs von den Lungen 6 (KL-6) (21), as well as a broad spectrum of inflammatory cytokines from admission to over six months after discharge. The gene discussed is MUC1; the disease is COVID-19.