Among them IL-6, CXCL10, CXCL11, and MCP-3 were markedly elevated at baseline, during, and after MP treatment; besides, the differences in all the cytokines between the two time points, before and after MP treatment, were not significant (Figure 4B), suggesting MP was not effective in improving these inflammatory markers associated with CRS. This evidence concerns the gene CXCL11 and congenital rubella syndrome.