IL2 and posterior cortical atrophy: Together with the GSVA results that multiple stroma-regulatory pathways (e.g. TGFβ, myogenesis, IL-6 and IL-2) were upregulated in WT tumors (Figure 1C), our data implied that m6A signaling disturbance caused by genomic alterations may impact PCa progression via, at least partially, reshaping the TME.