When overexpressed in cancer cells, ABCB1 produces an MDR phenotype to various chemotherapeutic drugs, including paclitaxel, doxorubicin, and tyrosine kinase inhibitors (TKIs) such as GSK-1070916 and TAK243 (Wu et al., 2020c; Wu et al., 2022). This evidence concerns the gene ABCB1 and cancer.