PTGS2 and respiratory system disorder: Prostaglandin-endoperoxide synthase 2(PTGS2), the official gene symbol for Cyclooxygenase 2(COX-2), which can be rapidly and robustly expressed in a variety of pro-inflammatory cytokines and mediators, was a pivotal factor in the pathobiology of respiratory diseases such as inflammatory dysregulation (Rumzhum and Ammit, 2016).