Among these, lnc-HILPDA and lnc-PRND, which were conservative and remarkably up-regulated in both kidneys and blood from rats and the blood of PC-AKI patients, can effectively predict PC-AKI risk and precisely distinguish PC-AKI patients after the exposure to contrast medium (Chen et al., 2021a). The gene discussed is PRND; the disease is pachyonychia congenita.