GAS5 and acute kidney injury: Another recent study has described that the lncRNA MEG3 could promote cisplatin-induced nephrotoxicity through regulating AKT/TSC/mTOR-mediated autophagy, and LncRNA GAS5 could aggravate renal epithelial cell apoptosis in cisplatin-induced AKI by regulating miR-205-5p (Jing et al., 2021; Zhang et al., 2021).