CD8A and colorectal cancer: We then performed a more detailed deconvolution of 22 immune cell types with CIBERSORTx (11), which showed significantly enriched scores for CD8+ T cells, memory resting CD4+ T cells, activated NK cells, DC cells, mast cells, and regulatory T cells (Treg cells) and, more notably, for macrophages in the MTA1-high group versus the MTA1-low group of colorectal cancers (Figure 1G).