We then evaluated the expression of astrocytic-related genes previously found altered during neuroinflammation and previously classified as A1 (LPS-induced) or A2 (stroke-induced).24,25 Compared with adult, aged sTBI mice showed elevated expression of the LPS-induced genes (H2-T23, H2-D1, Ggta1; P < 0.05, Fig. 7C–F) up to 7 days. Here, GGTA1 is linked to stroke disorder.