ASB2 and leukemia: In leukemia, FTO promoted the proliferation of AML cells by reducing m6A levels at the 3′-UTR of Asb2 and 3′ and 5′-UTR of Rara, two mediators of hematopoiesis and differentiation, resulting in decreased ASB2 and RARA protein expression (Li Z. et al., 2017).