While the role of METTL3 in promoting proliferation in many cancer types has been well-established, the role of METTL3 in pancreatic cancer proliferation remains controversial as two independent studies found contrasting roles for METTL3 in promoting pancreatic cancer cell proliferation (Taketo et al., 2018; Xia et al., 2019). The gene discussed is METTL3; the disease is familial pancreatic carcinoma.