In the current pandemic, Seow et al analyzed single-cell RNA sequencing in human liver tissues and identified co-expression of Angiotensin-Converting Enzyme 2 (ACE-2) and Transmembrane Serine Protease 2 Expression (TMPRS) in the Liver progenitor cells, which serves as entry receptor for COVID-19 Spike (S) protein resulting in Liver injury and associated abnormalities like hypoalbuminemia and elevated liver enzymes[13]. This evidence concerns the gene TMPRSS2 and Hypoalbuminemia.