In the clinical setting, sepsis diagnosis is defined by the appearance of multiple physiologic and biochemical abnormalities that may include decreased oxygen saturation, altered mental status, decreased systolic blood pressure, abnormal serum creatinine, lactate, C-reactive protein (CRP) and bilirubin, decreased platelet counts and coagulopathic changes such as increased D-dimer, thrombosis, or bleeding.17 The gene discussed is CRP; the disease is Sepsis.