Upon further analysis of this published data set generated in the mantle cell lymphoma cell line Rec-1, we found a consensus RBPj site within intron 2 of the IL21r locus, which showed strong binding of RBPj and MAML, as well as γ-secretase inhibitor–sensitive (GSI-sensitive) Notch1 binding (Supplemental Figure 2B). Here, NOTCH1 is linked to mantle cell lymphoma.