Similarly, 0 of 53 patients (0%) with autoimmune rheumatic diseases (25 patients with systemic lupus erythematosus [SLE], 13 with scleroderma, and 15 with autoimmune necrotizing myopathy) had IgM autoantibodies recognizing ACE2. The gene discussed is ACE2; the disease is systemic lupus erythematosus.