Seven variants in six genes were found in individuals with cardiovascular disease phenotypes, SCN5A c.2309C > T (p.Ala770Val), LMNA c.326 T > G (p.Val109Gly), MYBPC3 c.1021G > T (p.Gly341Cys), TPM1 c.674A > G (p.Tyr225Cys), DSP c.1841A > G (p.Asp614Gly) and c.7604A > G (p.Asp2535Gly), and RYR2 c.13919 T > C (p.Val4640Ala). The gene discussed is TPM1; the disease is cardiovascular disorder.