Secondary differential expression analyses comparing glaucoma to non-glaucoma samples within the same cohort identified 4 DEGs, 3 of which were also differentially expressed in the PEX versus non-PEX analysis (EGR2, FOSB, and EGR3), and one of which was uniquely differentially expressed in the glaucoma versus non-glaucoma analysis (USP6; Fig. 1C). Here, USP6 is linked to glaucoma.