2013; Soverini et al. 2018). The ability of stachydrine in targeting multiple RTKs makes it advantageous over Bcrl-Abl TKI. We previously identified that gallic acid, a plant extract from TCM, is effective against acute myeloid leukaemia (Gu et al. 2018). It is of interest to note that gallic acid also inhibits Bcr-Abl and Src signalling pathways in leukaemia and lung cancer (Chandramohan Reddy et al. 2012; Phan et al. 2016). Stachydrine and gallic acid are bioactive component of TCM. Increasing evidence has shown the various therapeutic activities of TCM in cancer (Xiang et al. 2019). This evidence concerns the gene SRC and acute myeloid leukemia.