After adjusting for randomization arm, HSV-2 serology, BV, and bacterial STIs at baseline to account for antibiotic exposure, participants who cleared Candida colonization experienced a decrease in IL-17F (β= −0.90; 95% CI, −1.8 to 0; P = 0.05) compared to those remaining colonized, while adolescents acquiring Candida colonization experienced a decrease in IL-17A (β= −0.60; 95% CI, −1.12 to −0.070; P = 0.027) compared to those who remained Candida-free, neither of which remained significant after accounting for multiple comparison (Fig. 6D). Here, IL17A is linked to sexually transmitted disease.