METTL3 and neoplasm: Furthermore, the expression of miR‐589‐5p in the tumour tissue was detected, as shown in Figure 7F, the expression of miR‐589‐5p in the tumour tissue was down‐regulated by METTL3 silencing but up‐regulated by miR‐589‐5p mimic (p < 0.01), and the effects of METTL3 silencing and miR‐589‐5p mimic on miR‐589‐5p were reversed by each other.