Furthermore, the clinicopathological characteristics of liver cancer patients with a high or low expression of METTL3 were analysed; from Table 2, it could be observed that a high level of METTL3 was associated with the tumour size (p = 0.008), Edmondson‐Steiner grading (p = 0.029) and TNM tumour stage (p = 0.003). This evidence concerns the gene METTL3 and liver cancer.