Programmed cell death ligand‐1 (PD‐L1) (another name: CD274 or B7‐H1) expression indicates a suppressed immunity system, which allows tumor escape immune attack, causing tumors cells to grow and metastasize,8 and it is the sole FDA‐authorized biomarker for LUAD sufferers treated by immune checkpoint inhibitors (ICIs).9 This evidence concerns the gene CD274 and neoplasm.