PD‐L1 protein level in fresh LUAD tissues derived from fiberoptic bronchoscopy biopsy was detected by IHC, and the positive result was shown as brown‐yellow granular staining of the cell membrane in tumor cells, and the results exhibited that 53.33% (32/60) of tissue samples presented PD‐L1 positive expression and 46.67% (28/60) of tissue samples showed no PD‐L1 expression (Figure 2A). The gene discussed is CD274; the disease is neoplasm.