SDC1 and COVID-19–associated multisystem inflammatory syndrome in children: We found that syndecan-1 median (IQR) concentration at admission was significantly elevated in all MIS-C patients as compared to healthy matched controls (144 [105–547] vs 50 [15–71] ng/mL; P = 0.001), with higher levels in MIS-C patients with shock as compared to MIS-C patients without shock, without reaching statistical significance (514 [122–1123] vs 113 [99–151] ng/mL; P = 0.2).