FOXA3 and asthma: The top FOXA3 eQTL (rs8103278), where the G allele is associated with increased asthma risk, was highly co-localized (PP4 = 0.97) with the FOXA3 COA GWAS locus (p = 1.1e–63, Fig. 5a), strengthening confidence that rs8103278 enhances asthma risk by upregulating this gene.