CD86 and neoplasm: Inhibitory DAMP blockade by both approaches consistently induced increased expression of maturation markers (i.e., CD40, CD86, H2-k) in BMDCs (Fig. 4g, red histograms), which was compared with LPS-stimulated BMDCs (as positive control) and untreated tumor cells (as NT negative control) (Fig. 4g, light gray and dark gray histograms, respectively).