Flow cytometry tumor analysis revealed increased CD45+ immune infiltration, and increased macrophage (CD45+ F4/80+) and NK (CD45+ NKp46) infiltration (Fig. 4C), but not a significant increase in infiltrating CD45+ CD11b+ cells (Fig. S5A), consistent with a degranulation phenotype rather than an antigen presenting phenotype. The gene discussed is NCR1; the disease is neoplasm.