RELA and non-small cell lung carcinoma: The cell growth assay revealed that knockdown of GLUT1 diminished the promoting effects of P65 overexpression and OVOL2 knockdown on cell survival (Fig. 7A, B), suggesting that GLUT1-mediated aerobic glycolysis is required for NF-κB signaling- and OVOL2-regulated NSCLC cell survival.