Since our results clearly demonstrated that OVOL2 inhibits NF-κB signaling-induced GLUT1 membrane expression and aerobic glycolysis and that OVOL2 is downregulated by NF-κB signaling in NSCLC cells, we further explored whether the expression patterns of OVOL2 and GLUT1 are critical for NF-κB signaling-induced NSCLC cell survival. Here, NFKB1 is linked to non-small cell lung carcinoma.