Studies have shown that STEAP1 can transfer an electron through the heme group to reduce Fe 3+ to Fe 2+ and Cu 2+ to Cu + to form homologous trimers or heterotrimers with STEAP2 [23], and promote copper absorption, this is consistent with the pathway in our KEGG analysis that STEAP1 and STEAP2 may play a role in cancer by forming functional complexes involved in the process of mineral absorption. The gene discussed is STEAP2; the disease is cancer.