Compared with PD-L1 negative expression group, higher proportions of IFN-gamma, CD8+ T cells, NK cells, NK CD56 dim cells, Th1 cells, Th2 cells (P < 0.0001) and lower percentage of NK CD56 bright cells and Th17 cells (P < 0.05) was observed in PD-L1 high expression group, supporting that high PD-L1 expression level can be a prognostic marker for anti-cancer immunotherapy. Here, IFNG is linked to cancer.