We meta-analyzed 728 patients from four studies and discovered that PROX1 expression in GC patients is not related to tumor size (≥ 5 cm and < 5 cm) (OR: 0.889, 95% CI 0.502–1.576, P = 0.687) (Fig. 6 and Additional file 1: Table S1). This evidence concerns the gene PROX1 and neoplasm.