The possible association of the ALDH2 genotypes with potential risk factors for hypertension were based on three genetic modes of inheritance, such as the co-dominant mode (ALDH2 G/A vs. ALDH2 G/G, ALDH2 A/A vs. ALDH2 G/G), dominant mode (ALDH2 G/A plus ALDH2 A/A vs. ALDH2 G/G), and recessive mode (ALDH2 A/A vs. ALDH2 G/G plus ALDH2 G/A) models. This evidence concerns the gene ALDH2 and Hypertension.