Indeed, aberrant SKP1 expression and/or function is already associated with several human genetic disorders, including Sjögren’s syndrome (a chronic inflammatory autoimmune disease) (Sandhya and Danda, 2014), sporadic Parkinson’s disease (a neurological degenerative disorder) (Mandel et al., 2012) and cancer (Silverman et al., 2012). This evidence concerns the gene SKP1 and cancer.