Carcinoembryonic antigen cell adhesion molecule 1 also similarly releases Bat3 from TIM3 upon binding to TIM3 to inhibit T cell receptor (TCR) signaling, and is expressed on activated T cells, DCs, monocytes, macrophages, and tumor cells (Acharya et al., 2020). The gene discussed is HAVCR2; the disease is neoplasm.