In 2017, Lee et al. found that simvastatin was able to promote the antifibrotic properties associated with the early perfusion of apoptotic cells in the middle stage of bleomycin-induced pulmonary fibrosis in mice, and the combined action of simvastatin and the administration of apoptotic cells further enhanced the expression of PPAR-γ in alveolar macrophages and inhibited the pulmonary fibrotic response [101]. Here, PPARG is linked to pulmonary fibrosis.