One the one hand, Cox proportional hazards model analysis illustrated that the expression levels of GPC2 were associated with OS in COAD (p < 0.001), PAAD (p < 0.001), acute myeloid leukemia (LAML) (p < 0.001), ACC (p < 0.001), SARC (p < 0.001), KIRC (p < 0.001), BLCA (p = 0.001), PRAD (p = 0.003), brain lower grade glioma (LGG) (p = 0.003), HNSC (p = 0.005), mesothelioma (MESO) (p = 0.005), THYM (p = 0.009), LIHC (p = 0.013), ESCA (p = 0.016), BRCA (p = 0.035), UCEC (p = 0.035), uveal melanoma (UVM) (p = 0.049), and THCA (p = 0.049) (Figure 5). This evidence concerns the gene GPC2 and mesothelioma.