GPC2 and cancer: In the examination on the tumor stage relevance, we discovered it was in 16 types of cancer that the GPC2 expression significantly increased in the early tumor stage (Figure 3), including CHOL, LUSC, LUAD, KIRP, HNSC, LIHC, ESCA, KIRC, UCEC, BLCA, COAD, READ, STAD, PRAD, THCA, and BRCA, indicating that GPC2 may have important clinical value in the early diagnosis of these tumors.