As expected, no significant publication bias was detected by Begg's funnel plot for the association between TNF- α-308G/A gene polymorphism and liver cirrhosis expected (GA vs. GG, P = 0.675; AA vs. GG, P = 0.261; GA + AA vs. GG, P = 0.866; and AA vs. GA + GG, P = 0.199) (Figure 5). The gene discussed is TNF; the disease is cirrhosis of liver.