In both blood and nasal samples, the most presented differentially methylated loci were annotated to ACOT7, EPX, KCNH2, SIGLEC8, TNIK, FOXP1, ATPAF2, ZNF862, ADORA3, ARID3A, IL5RA, METRNL, ZFPM1, making them possible candidates for allergic respiratory disease biomarkers. This evidence concerns the gene ATPAF2 and allergic respiratory disease.