Overlapping DMRs across phenotypes.More DMRS for FENO• Th2 activation and eosinophilia (EPX, IL4, IL13, PRG2, CLC, ZFMP1)• Solute carriers and intracellular transport genes (SLC25A25, SLC39A4, DNAH17, VTI1A)• T cell activation (LAX)• Oxidative stress (VKORC1L1)• Mucin production (GALNT7).• Gap junction protein gene (GJA4)• 53% replicated CpGs “inner city Consortium”• 61% replicated CpGs “EVA‐PR” studies. Here, CLC is linked to Increased total eosinophil count.