The primary outcomes were various clinical indicators for coronary artery disease, namely, angina frequency (AF), angina stability (AS), disease perception, physical limitation (PL), treatment satisfaction (TS), anxiety and depression levels (evaluated by the scores on the Self-Rating Anxiety Scale scores [SAS], and Self-Rating Depression Scale scores [SDS]); serum indicators, including interleukin-6 (IL-6), low-density lipoprotein cholesterol (LDL-C), cereal third transaminase, blood urea nitrogen, and creatinine; and white blood cell count. The gene discussed is IL6; the disease is major depressive disorder.