As reported, the miR-200 family was remarkably decreased within gemcitabine resistant pancreatic tumor cells and the upregulation of the miR-200 family could reverse the EMT (epithelial–mesenchymal transition).32 miR-34 is involved in cancer stem cell maintenance and survival through the regulation of Notch pathway proteins and Bcl-2. Here, BCL2 is linked to pancreatic neoplasm.