Consistently, confocal microscope-based fluorescence in situ hybridization (FISH) analysis of lncRNA-CGB and immunofluorescent staining of EZH2 showed that significant amounts of EZH2 co-localized with lncRNA-CGB in the nucleus of CD3 + T cells from patients with active TB (Figure 7d). This evidence concerns the gene EZH2 and tuberculosis.