IFNG and tuberculosis: Furthermore, oral transfer of the resident intestinal probiotic Bacteroides fragilis (B. fragilis) sustained expression of lncRNA-CGB, and promoted anti-TB immune protection via epigenetically modulating IFN-γ expression, indicating that a selected lncRNA signature modulated by commensal gut bacteria might be a key mediator regulating gut-lung axis homeostasis during M. tuberculosis infection.