CD14 and tuberculosis: To confirm whether human lncRNA-CGB also played a role in mediating anti-TB resistance as mouse lncRNA-CGB did, we developed a human T cell adoptive transfer-based M. tuberculosis infection therapeutics study model with lncRNA-CGB knock-down in CD3 + T cells, as we previously did.28 Briefly, CD3 + T cells and CD14+ monocytes purified from PBMCs of active TB patients were firstly transduced with lentiviral (LV) vector encoding shRNA targeting lncRNA-CGB or LV vector only (LV-Ctrl).