Hence, it is possible that in the altered molecular context in gastric cancer cells, HACE1‐Rac1‐NADPH functional pathway, HACE1‐NRF2‐antioxidant proteins pathways and the HACE1‐mitophagy pathway are perturbed, or other pathways may become dominant to prevent their unfavourable effect for cancer growth. Here, DECR1 is linked to gastric cancer.