Notably, we detected that GPR65 expression was only positively relevance with the expression of IFN‐γ and IL17A (Figure S2G,H), implying that an increase of GPR65 mRNA is mainly ascribed to high level of IFN‐γ+ and IL17A+ cells in inflamed mucosa of IBD patients, which is consistent with the recent report.32 This evidence concerns the gene IL17A and inflammatory bowel disease.