↓ Incidence of lung tumors (males), ↓ Liver degeneration (both sexes) and ↓ Glomerulosclerosis (females) (Harrison et al., 2019)↓ Age‐related behavioral and biochemical changes in SAMP8 mice (Tong et al., 2015)↓ Age‐related memory impairment (Yan et al., 2015)↓ tumor burden and hematocrit in Apc +/Min mouse model of intestinal tumorigenesis at the higher dose (Dodds et al., 2020). This evidence concerns the gene APC and memory impairment.