In our population we found that statin therapy at admission did not influence the development of CIN in overall population, while, there was a significant interaction between KIF 6 polymorphism, statin therapy and CIN development, suggesting that the nefro-protective effects of these drugs could be even more relevant in carriers of the KIF-6 variant allele. Here, KIF6 is linked to cervical squamous intraepithelial neoplasia.