CCNE1 and neoplasm: After 25 days of injection, the mice treated with miR-106b-5p sponge presented a smaller tumor burden than controls by IHC (Figures 6(a) and 6(c)) and displayed lower expression for Ki67, proliferating cell nuclear antigen (PCNA), Bcl-xL, and cyclin E1, along with a higher expression for BTG3 in tumor tissues relative to controls by western blotting (Figures 6(d) and 6(e)).