IDH1 and cancer: Introduction to the market of a unique specific antibody directed against isocitrate dehydrogenase 1 (IDH1) mutated in codon 132 (IDH1R132H), a specific marker of glioblastoma arising from lower-grade tumors [117, 118] and application of this antibody in described method are enabled to prove that senescence occurs in cancer cells, not normal cells infiltrating the tumor [119].