The ontogeny, localization, expression, and function of ABCC1 in HCC were reported in several research studies, and the previous reports mainly focused on the role of ABCC1 in HCC drug resistance (Flens et al., 1996; Nies et al., 2001; Vander Borght et al., 2005). The gene discussed is ABCC1; the disease is hepatocellular carcinoma.