AKT1 and Familial prostate cancer: Moreover, as shown in Figures 7H,I, XHP could suppress the Akt (p = 0.024), p-PI3K(p = 0.000), p-Akt (p = 0.000), and p-mTOR (p = 0.000) protein of the PC3 prostate cancer subcutaneous transplantation significantly (p < 0.05) (t-test).